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Intro
Confused about blood cell types? Don't panic ... you're not alone! Even these cells seem to be having an identity crisis.
(You'll find this actual neutrophil on slide 22.) |
A Comparison of Terms
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KUMC Syllabus |
Junqueira |
Wheater |
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Rubriblast |
Proerythroblast |
Proerythroblast |
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Prorubricyte |
Basophilic Erythroblast |
Early Normoblast |
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Rubricyte |
Polychromatophilic Erythroblast |
Intermediate Normoblast |
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Metarubricyte |
Orthochromatophilic Erythroblast |
Late Normoblast |
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Reticulocyte |
Reticulocyte |
Reticulocyte |
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Slide 1: Bone Marrow
Recall that erythrocytes (RBCs) are about 7 to 8 microns. Learn to use them as the tissue's "built-in" scale bars. Neutrophils (green) Neutrophilic Metamyelocyte (blue)
Bar = 30 Microns |
 |
Slide 2: Bone Marrow
Prorubricyte (blue), Band neutrophil (red), Platelets (yellow), Platelets are cell fragments produced by megakaryocytes. You will see a few of them on most of the slides.
Bar = 30 Microns |
 |
Slide 3: Bone Marrow
Band (yellow)
Neutrophils (green)
Metarubricyte (red)
Bar = 30 Microns |
 |
Slide 4: Bone Marrow
Rubriblast (green)
Rubricytes (red)
Neutrophilic Myelocyte (yellow)
Bar = 30 Microns |
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Slide 5: Bone Marrow
Myeloblast (blue)
Neutrophil (green)
Bar = 30 Microns |
 |
Slide 7: Bone Marrow
At a lower power, you can see how the megakaryocyte is many times larger than the other blood cells.
Bar = 50 Microns |
 |
Slide 8: Bone Marrow
Myeloblast (blue)
Neutrophilic Metamyelocyte (yellow)
Promyelocyte (black)
Neutrophils (green)
Metarubricyte (red)
Bar = 30 Microns |
 |
Slide 9: Bone Marrow
Notice the granules in the cytoplasm of the promyelocytes (yellow). Plasma cells (blue) are commonly seen in peripheral tissues where they secrete antibodies.
Bar = 30 Microns |
 |
Slide 10: Bone Marrow
Neutrophil (green)
metarubricyte (red)
rubricyte (yellow)
plasma cell (blue)
Bar = 30 Microns |
 |
Slide 11: Bone Marrow
Band neutrophil (yellow)
Promyelocyte (red)
Neutrophilic metamyelocyte (blue)
Neutrophils (green)
Bar = 50 Microns |
 |
Slide 12: Bone Marrow
Eosinophilic metamyelocyte (Red)
Neutrophilic myelocyte (yellow)
Metarubricytes (Blue)
Bar = 50 Microns |
 |
Slide 13: Bone Marrow
Band eosinophil (Red)
Neutrophilic metamyelocyte (yellow)
Metarubricytes (Blue)
Bar = 50 Microns |
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Slide 14: Bone Marrow
Eosinophil (Red)
Neutrophil (yellow)
Bar = 50 Microns |
 |
Slide 15: Blood Smear
Monocytes are motile and phagocytic. In fact, they are the precursors to the macrophage. Notice how much larger they are than the red cells.
Bar = 30 Microns |
 |
Slide 16: Blood Smear
You can see how the nucleus of this monocyte is shaped somewhat like a horseshoe.
Bar = 30 Microns |
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Slide 17: Blood Smear
Band neutrophil (blue)
Small Lymphocyte (green)
Notice that the small lymphocyte is about the same size as the RBC.
Bar = 30 Microns |
 |
Slide 18: Blood Smear
Neutrophils (green)
Lymphocyte (yellow)
In this lower power view, notice how few white cells there are in this field of reds.
Bar = 50 Microns |
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Slide 19: Blood Smear
Neutrophils (green)
Lymphocyte (yellow)
Bar = 50 Microns |
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Slide 20: Blood Smear
Neutrophils (green)
Monocyte (blue)
Notice the horseshoe shaped nucleus of the monocyte.
Bar = 50 Microns |
 |
Slide 21: Blood Smear
This medium to large lymphocyte is about twice as large as the RBC.
Bar = 50 Microns |
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Slide 22: Blood Smear
Medium Lymphocyte (yellow)
Neutrophils (green)
Bar = 50 Microns |
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Slide 23: Blood Smear
Myeloblast to Promyelocyte transition (yellow)
Promyelocytes (blue)
Band (red)
Segmented Neutrophil (green)
Plasma Cells (black)
Notice the prominent granules in the promyelocyte.
Bar = 30 Microns |
 |
Slide 24: Blood Smear
Again the small lymphocyte is about the same size as the RBC.
Bar = 30 Microns |
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Slide 25: Blood Smear
The medium to large lymphocyte is about twice the size of the RBC
Bar = 30 Microns |
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Slide 26: Blood Smear
Neutrophils (green)
Bar = 50 Microns |
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And Finally...
You've made it! You should be proud of yourself ... these cells seem happy for you anyway. Go back and spend some time on the erythroid and myeloid series and be comfortable with the stages.
(By the way, you'll find this actual neutrophil on slide 10.) |
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